‘Green’ …yet wasting energy?: Mitochondrial respiration in plants

Cisplatin cytotoxicity is dependent on mitochondrial respiration in Saccharomyces cerevisiae

Objective(s): To understand the role of mitochondrial respiration in cisplatin sensitivity, we have employed wild-type and mitochondrial DNA depleted Rho0 yeast cells. Materials and Methods: Wild type and Rho0 yeast cultured in fermentable and non-fermentable sugar containing media, were studied for their sensitivity against cisplatin by monitoring growth curves, oxygen consumption, pH changes ...

Respiration in Plants

Respiration in blue-green algae.

The low rate of endogenous respiration exhibited by the blue-green algae Anacystis nidulans and Phormidium luridum was not increased by the addition of respiratory substrates. However, endogenous respiration was inhibited by low concentrations of cyanide and by high carbon monoxide tensions. In addition, the uncouplers dinitrophenol and carbonyl cyanide p-trifluoromethoxyphenylhydrazone both st...

Circadian rhythms in mitochondrial respiration

Many physiological processes are regulated with a 24-h periodicity to anticipate the environmental changes of daytime to nighttime and vice versa. These 24-h regulations, commonly termed circadian rhythms, among others control the sleep-wake cycle, locomotor activity and preparation for food availability during the active phase (daytime for humans and nighttime for nocturnal animals). Disturbin...

Mitochondrial Respiration and Atherosclerosis

Atherosclerosis is an underlying cause of various cardiovascular diseases including coronary artery disease, chronic kidney disease, abdominal aortic aneurysm development, stroke, and heart failure. This progressive vascular disease is characterized by subendothelial lipoprotein retention, immune cell infiltration, a maladaptive inflammatory response, and vascular smooth muscle cell (VSMC)–medi...